Acute myelogenous leukemia (AML) is a type of cancer that affects the blood-forming cells in an individual’s bone marrow. It may adversely affect the white blood cells, red blood cells, and platelets. The actual cause of the disease is unknown, but genetic or blood disorders, previous cancer treatments, or prolonged radiation exposure are considered to be some of the risk factors. Recognizing these early warning signs of AML is crucial for timely intervention and treatment. Warning signs of AML Like many cancers, AML often starts with subtle symptoms that may be mistaken for other, less severe conditions. Here are some of these warning signs that should prompt one to seek medical help. Bone and joint pain Some individuals with AML experience bone and joint pain, which may be mistaken for arthritis. This pain typically occurs in the long bones of the arms and legs. Swelling of the abdomen Enlargement of the spleen or liver, which can occur in AML, may cause abdominal discomfort or a feeling of fullness. Fatigue and loss of appetite Unexplained and persistent fatigue or weakness is a common early sign of AML. It occurs because the body cannot produce enough healthy red blood cells, reducing oxygen supply to tissues and muscles.